Your family begins here
Southeastern Center for Fertility & Reproductive Surgery
865.777.0088     Jeffrey A. Keenan, MD, HCLD, Director

Dr. Keenan - Compassion and competence are two traits I routinely see fading from the medical field. Your office was a glimmer of hope that it does still exist.

P.S., Lake Lure, North Carolina

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I just have a question I think I have hormonal problems I think I need IVF I am having irregular cycles I think I need surgery I am having pelvic pain I am having miscarriages I am trying to get pregnant

The Southeastern Center for Fertility and Reproductive Surgery offers this site as an information resource for couples coping with the difficulties of infertility. Just as our center provides the most advanced treatment for our patients, this site provides the most recent and accurate medical information concerning infertility and reproductive surgery.

Located in Knoxville, Tennessee, the center specializes in the diagnosis and treatment of male and female infertility problems. Under the direction of Jeffrey A. Keenan MD, HCLD, our patients receive the highest quality medical care available in the region. Dr. Keenan is one of the most experienced and respected specialists in infertility and reproductive medicine and surgery.

We provide updates on this site to ensure you are receiving the latest information. If you wish to schedule an appointment with us or have questions, please call us at (865) 777-0088 or click here to use our appointment request form.

Dr. Jeffrey A. Keenan



Special Announcement

Dear Patient,

Our desire is to help as many patients as possible with their medical care; therefore, we have not increased our charges in several years. Unfortunately, the cost of doing business has increased by over 7% since the last time our fees increased. In order for us to continue providing quality services for you at the advanced levels that you have come to expect, a 5% increase is necessary and has been implemented effective May 1, 2014.

We want to assure you that despite these changes, our goal to help as many patients as possible has not changed. Even with the increase, our fees are almost always considerably lower than those found in other specialty practices such as ours. Furthermore, we remain committed to assisting our patients whenever possible when financial hardships arise. If you have any questions or require our assistance, please contact us.


Juliana Stanley, Practice Manager

Summer Update 2014

Summer is finally here! Although summer is a busy period, don't forget to take some "me time" and schedule that well woman visit you've been putting off, or take the time to finally pursue infertility treatment for the baby you've been wanting. Our front office coordinator, Bonita, would be pleased to assist you at (865)777-0088. Call today for an appointment!

Welcome Venissa Ebel, LPN

Please, join us in welcoming our new IVF nurse, Venissa Ebel. Venissa is originally from Cincinnati, Ohio and has been a nurse since 2009. She has worked previously in long-term care where she took care of ventilator patients as well as in primary care and in an allergy office. She has been working hard to learn the responsibilities of her new position, and is proving to be an integral part of our staff. Venissa is always welcoming and would be happy to answer any of your questions with a smile. Give her a call today!

Cheaper Tubal Reversals!

Do you regret having your tubes tied? Are you looking into a tubal reversal but have felt that the procedure is just too expensive? Well, then we have good news for you! The Southeastern Center for Fertility and Reproductive Surgery is pleased to announce that, along with Turkey Creek Medical Center, we have reduced our tubal reversal fees by more than 25%! The total cost is now $6,000 for patients of normal weight. If you would like more information regarding reversal of sterilization, visit our tubal reversal website at

Infertility and Pregnancy Loss Resources

Did you know that there are several resources for those dealing with infertility and pregnancy loss? Many of these are provided through Bethany Christian Services, which is a global nonprofit family preservation and child welfare organization caring for orphans and vulnerable children on five continents. Stepping Stones provides couples with Christian support and encouragement when facing infertility or pregnancy loss. Sarah's Laughter provides support for those struggling with infertility or the death of a baby. Dancing Upon Barren Land is an online, Christian support ministry addressing the needs of those suffering through infertility. Hannah's Prayer Ministries provides Christian-based support and encouragement to married women around the world who are struggling with the pain of fertility challenges, including primary and secondary infertility, pregnancy loss, early infant death, and adoption loss. If you'd like to learn more about these resources, you can find links to their pages on our webpage:

Literature Review

Woman Achieves Pregnancy After Removal of Both Ovaries!

A study published in Human Reproduction identifies a woman who achieves a twin pregnancy following grafting of ovarian tissue onto the abdominal wall.

Cryopreservation (freezing) of ovarian tissue is an option for young women at risk of losing ovarian function following cancer treatment. Typically, the tissue is grafted back onto an orthotopic site, which would be a structure inside the pelvis near where the ovaries are normally located. In the event that there is not an appropriate orthotopic site for grafting due to pelvic adhesions, for example, a heterotopic site may be chosen. This would involve a site that is distant to the ovary such as the abdominal wall, forearm, or breast. Heterotopic sites may not provide an optimal environment for egg maturity due to differences in temperature, hormonal factors, and blood supply compared to the normal pelvic environment. Until this study, there have been no clinical pregnancies reported after heterotopic grafting.

This particular patient had her left ovary removed at 21 years of age due to a tumor, followed 4 years later by removal of her right ovary. Prior to her second surgery, she opted for cryopreservation of her ovarian tissue. Seven years later, the patient sought fertility assistance and the previously frozen ovarian tissue was grafted onto her abdominal wall. She required grafts on two separate occasions following eventual failure of the first graft, but was noted to have ovarian activity. The patient then underwent in vitro fertilization (IVF) and conceived twins, thus proving that normal ovarian function and pregnancy can occur at a nonovarian site.

Obesity Seems to Affect Everything!

A recent study in Fertility and Sterility has found that pregnancy and live-birth rates are significantly reduced as Body Mass Index (BMI) increases, probably due to reduced uterine receptivity. Various studies have already demonstrated an increase in infertility in obese women, even when they ovulate regularly. It is also known that miscarriage rates and pregnancy complications are also higher in this population.

During this study, 9,587 cycles of egg donation with eggs from normal weight donors were analyzed. They found that obese women, especially those with polycystic ovarian syndrome (PCOS), seem to have endometrial dysfunction compared with their normal weight counterparts. In addition, for every increased BMI unit, there was a 1.08% decrease in the probability of becoming pregnant. This study demonstrates that uterine receptivity seems to be altered in obese egg recipients, leading to reduced implantation and pregnancy rates, as well as lower live-birth rates. Overall, obesity probably affects all the components of the reproductive system including: sperm, egg, embryo, and uterus. Thus, weight reduction is advisable prior to natural or assisted conception, whether with a patient's own or donated eggs.